The 28-year-old, who gave birth to daughter Kulture in 2018, wore an embellished black bodysuit to the event to show off her baby bump. The rhinestone-encrusted gown had a sheer panel in the abdomen area that revealed her belly.
Offset wore a blingy pair of trousers with a black jacket over a white tee.
During a performance on Saturday Night Live in 2018, the mother-to-be revealed her first pregnancy.
Cardi B and Offset got hitched in September 2017. She filed for divorce in September 2020, after three years of their on-and-off marriage. By November, the couple had reconciled and were enjoyed a romantic vacation for Valentine's Day.
Here are some of the stand-out photos from the ceremony.
See Full list of winners
Video of the year: Cardi B ft. Megan Thee Stallion - WAP
Best female R&B/pop artist: H.E.R.
Best male R&B/pop artist: Chris Brown
Best female hip-hop artist: Megan Thee Stallion
Best male hip-hop artist: Lil Baby
Best new artist: Giveon
Best group: Bruno Mars, Anderson .Paak & Silk Sonic
Best collaboration: Cardi B featuring Megan Thee Stallion - WAP
Album of the year: Jazmine Sullivan - Heaux Tales
Viewer's Choice Award: Megan Thee Stallion ft Beyoncé - Savage (Remix)
Lifetime Achievement Award: Queen Latifah
Best gospel/inspirational Award: Kirk Franklin - Strong God
BET HER Award: SZA - Good Day
Video director of the year: Bruno Mars and Florent Déchard - Keep the Door Open
Best actress: Andra Day
Best actor: Chadwick Boseman
Best movie: Judas and the Black Messiah
Youngstars award: Marsai Martin
Sportswoman of the year: Naomi Osaka
Sportsman of the year: LeBron James
Best international act: Burna Boy (Nigeria)
Best new international act: Bree Runway (UK)