Based on a true story, The Social Network Zuckerberg played by Jesse Eisenberg turned a foe with his friend, Eduardo Saverin played by Andrew Garfield.
Michael B. Jordan's character Donnie in Creed III develops some bitterness with old friend Dame played by Jonathan Majors.
Started as best friends in X-Men: First Class, Carles Xavier (James McAvoy) and Erik Lehnsherr (Michael Fassbender) parted ways due to differing opinions.
Best friend Peter Parker & Harry became arch-rivals in Spider-Man 3 after Harry finds that Peter is the real spiderman who killed his father 'The Green Goblin'.
Varun Dhawan and Sidharth Malhotra first start as competitors in Student of the Year but later become friends, however, then again they break their friendship.
Ranbir Kapoor's character Bunny becomes distant as a friend, especially from Aditya Roy Kapur's character Avi in Yeh Jawaani Hai Deewani.
Sushant Singh Rajput & Rajkummar Rao's character turn from friend to foes after Kumar's character becomes close to Sushant's sister in Kai Po Che!
Once best friends, Tony Stark & Steve Rogers's relationship became bitter in Captain America: Civil War due to the 'Winter Soldier'.